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Clinical trials have shown that doses ranging from 250mg to 500mg per day, taken over 12 weeks, can lead to: A measurable reduction in the melanin index (the darkness of the skin)

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mEPSCs were recorded form mRFP ⁇ -actin transfected hippocampal neurons treated for 5 days with Hinge (10 "12 M), HGF (10 ng/ml), Dihexa (10 "12 M), Hinge + HGF (10 "S 2 M + 10 ng/ml, respectively) or Hinge + Dihexa (10 "12 M each)