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Its use is therefore restricted to the intensive care unit making this agent an adjunct therapy for refractory cases of AWS.3, 6, 80, 90, 91 Its application and experience in AWS is limited to only a few cases and rebound of withdrawal symptoms soon after stopping propofol infusion has been reported.10 Barbiturates Barbiturates are also GABA‐enhancing drugs that work synergistically with BZD featuring a different receptor profile
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