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Urinary DA was similar in untreated mice of both strains but was increased by etamicastat in D 2 −/− but not D 2 +/+ mice (Fig

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However, the decrease in NRF1 and TFAM expression in the skeletal muscles and TFAM expression in kidneys of GHRKO mice was also demonstrated ( TFAM may reflect potentially unaltered mtDNA content in GHRKO mice ( However, several recent findings are different from the previous results